2020  

Ling Rao, Victor Mak, Yuan Zhou, Dong Zhang, Xinran Li, Chloe Fung, Rakesh Sharma, Chao Gu, Yiling Lu, George Tipoe, Annie NY Cheung, Gordon Mills, and Lydia Cheung* (2020). p85β regulates autophagic degradation of AXL to activate oncogenic signaling. Nature Communications (Just accepted) (IF 12.1)

Martin Cheung*, Xintao Yang, Feng Hu, Jessica Liu, Shan Yu, May Cheung, Xuelai Liu, Irene Oi-Lin Ng, Xin-Yuan Guan, Kelvin Wong, Rakesh Sharma, Hong Lok Lung, Yufei Jiao, and Leo Lee (2020). Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma. Oncogene (Just accepted) (IF 6.6)

Bailiang He , Nelson Ng , Ning Yang , Chae-Yin Cher , Ho-Ching Leung ,Leo Kan , Bowie Cheng , Stephen Lam , Michelle Wang , Chunxiao Zhang , Hin Kwok , Grace Cheng , Rakesh Sharma ,  Alvin Ma , Eric So , Yok-Lam Kwong and AYH Leung * (2020). Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia. EMBO Molecular Medicine ( In Press) (IF 10.6)

 

2019  (4 papers)

 

Zhou, XD., Yu, Zheng., Sharma, R., Zhang, ZJ*  (2019). Total Polysaccharides of Lily Bulb Ameliorate Menopause-Like Behavior in Ovariectomized Mice: Multiple Mechanisms Distinct from Estrogen Therapy. Oxidative Medicine and Cellular Longevity, vol. 2019, Article ID 6869350, 27 pg.DOI:10.1155/2019/6869350 (IF 4.8)

Chen, R R., Yung, M M H., Xuan, Y., Zhan, S., Leung, L L., Liang, R R., Leung, T H Y., Yang, H., Dakang, Xu., Sharma, R., Chan, K K L., Ngu, S-F., Ngan, H Y S*., Chan, D W* (2019). Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells. Communications Biology. DOI: 10.1038/s42003-019-0508-1 

Liu, F., Seto W. K.,* Wong D. KH.,* Huang FY., Cheung, KS., Mak, LY., Sharma, R.,  Zhang, S., Fung, J.,  Lai, CL., Yuen, MF (2019). Plasma fibronectin levels identified via quantitative proteomics profiling predicts hepatitis B surface antigen seroclearance in chronic hepatitis B. The Journal of Infectious Diseases. May 6, 2019 pii: jiz223. DOI: 10.1093/infdis/jiz223 (IF 5.1)

Li, Xinran., Mak, V., Zhou, Y., Wang, C., Wong, E., Sharma, R., Lu, Y., Cheung, A NY., Mills, G., Cheung, L* (2019).  Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer. Nature Communications. Feb 12. DOI: 10.1038/s41467-019-08574-7.(IF 12.1)

 

2018 (3 papers)

 

Chan, LH*., Zhou, L*., Ng, KY*., Wong, TL*., Lee, TK., Sharma, R., Loong, JH., Ching, YP,, Yuan, YF., Xie, D., Lo, CM., Man, K., Artegiani, B., Clevers, H., Yan, HH., Leung, SY., Richard, S., Guan, XY., Huen, MS., Ma S. (2018) Protein arginine methyltransferase PRMT6 regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation. Cell Rep; October 16, 2018 DOI:10.1016/j.celrep.2018.09.053. (IF 8.0)   

Wong, OGW., Yang, Cheung CL., Ip, PPC., Ngan, HYS., Cheung, ANY. (2018) Amyloid Precursor Protein Overexpression in Down Syndrome Trophoblast Reduces Cell Invasiveness and Interferes with Syncytialization. Am J Pathol. 2018 Jul 20. pii: S0002-9440(17)30904-5 (IF 4.2)

Ying, Zhang., Chi, Xiong., Mateusz, Kudelko., Yan, Li., Cheng, Wang., Y Lun, Wong., Vivian, Tam., Muhammad, Farooq Rai., James, Cheverude., HA, Lawson., Linda, Sandell., WCW, Chan., KSE, Cheah., PC, Sham., Danny, Chan. (2018) Early-onset disc degeneration in SM/J mice is associated with ion transport systems and fibrotic changes. Matrix Biology 9; pii: S0945-053X(18)30076-3 (IF 7.4)

 

2016 & 2017 (2 Papers) 

 

Liu, AJ., RAO, Y., Cheung, MPL., Hui, MN., Wu, MH., Chan, LK., Ng, IOL., Niu, B., Cheah, KSE., Sharma, R., Hodgson, L., Cheung, MCH (2017). Asymmetric localization of Dlc1 defines trunk neural crest polarity for directional delamination and migration. Nature Communications 30; 8(1):1185 (IF 12.1)

Kudelko, M., Chan, CWL., Sharma, R., Yao, Q., Lau, E., Chu, IK., Cheah, KSE., Tanner, JA., Chan, D. (2016) Label-free quantitative proteomics reveals survival approaches developed by hypertrophic chondrocytes under ER stress. Journal of Proteome Research 4; 15(1):86-99. (IF 4.1)