Dionex UltiMate 3000 RSLC nano Liquid Chromatography and Orbitrap Fusion Lumos Tribid Mass Spectrometer


The ThermoScientific Orbitrap Fusion Lumos is coupled to Dionex Ultimate 3000 RSLC nano system. Lumos combines quadrupole, Orbitrap, and ion trap mass analyzers into a single instrument that provides the ultimate in data acquisition flexibility and utility. The OrbiTrap analyzer can obtain data at resolutions ranging from 15,000 to 450,000 (at m/z 200) with mass accuracy of <1 ppm. The unique  data acquisition strategies allows the Fusion to acquire data at an amazing 20 Hz with the ion trap MSn analyses and 15 Hz with the Orbitrap


  • Synchronous precursor selection (SPS) for selecting MS2 precursors for MS3 analysis. This feature decreases the effects of precursor co-isolation during MS1 to increase quantification accuracy for TMT and iTRAQ experiments.
  • The Fusion is equipped with collision induced dissociation (CID), higher energy collision induced dissociation (HCD), and electron transfer dissociation (ETD) and EthcD available at any stage of MSn with detection in either the Orbitrap or linear ion trap detector.